Tagline: If you follow the instructions, what could go wrong?
Genre: Horror,Drama,Science Fiction
Director: Coralie Fargeat
Cast: Demi Moore,Margaret Qualley,Dennis Quaid,Edward Hamilton-Clark,Gore Abrams,Oscar Lesage,Christian Erickson,Robin Greer,Tom Morton,Hugo Diego Garcia,Daniel Knight,Jonathon Carley,Jiselle Henderkott,Akil Wingate,Vincent Colombe,Billy Bentley,Lennard Ridsdale,Jordan Ford Silver,Oscar Salem,Viviane Bossina,Matthew Luret,Jana Bittnerová,Olivier Raynal,Tiffany Hofstetter,Nicolas Royer,Nathan Rippy,Manon Arizmendi,Virginie Kotlinski,Brett Gillen,Charlotte Marquardt,Léa Hengl,Gaëlle Raymond,Claire Lemaire,Lila Boughoufala,Aurélien Lorgnier,Ivan Sellier,Philip Schurer,Christian Bourmier,Martin Graham,Christian Bordeleau,Patrick Hamel,Didier D'Hondt,Jacques-Yves Dorges,Jean-Claude Matthey,Olivier Jarcin,Jean-Luc Magneron,Charlotte Murray,Aaron Kahn,Gabriela Arnon,Nancy Josephson Lahoussine,Andrew Eldridge,Denise Powers,Bryan Jones,Adam Carage,Maria McClurg,Andrew Desmond,Rebecca Lafont,Laura Puech,Ryan Chidester,Céline Vogt,Yannick Guérin,Jean Miel,Paul Descoings,Benoit Lévêque,Arthur Molinet,Manon Sachot,Bastien Jorelle,Kelly Hoarau,Michel Juskiewicz,Louise Greggory,Christophe Sartirano,Florent Torres,Romain Caldeira,Barthelemy Thomas,Axel Baille,Ashley Lambert,Ranjani Brow,Chase Fein,Shane Sweet,William Calvert,Michael Corbett,Stephen Apostolina,Yann Bean,Matthew Géczy,Namory Bakayoko,Gregory Defleur
Status: Released
Release: 2024-09-07
Runtime: 141
Plot: A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Trailer Cast Crew Videos
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Demi Moore
Elisabeth -
Margaret Qualley
Sue -
Dennis Quaid
Harvey -
Edward Hamilton-Clark
Fred -
Gore Abrams
Oliver -
Oscar Lesage
Troy -
Christian Erickson
Man at Diner -
Robin Greer
Male Nurse -
Tom Morton
Doctor -
Hugo Diego Garcia
Diego - Boyfriend -
Daniel Knight
Casting Director -
Jonathon Carley
Assistant Casting Director -
Jiselle Henderkott
Girl Auditioning -
Akil Wingate
TV Host -
Vincent Colombe
Man in Suit #1 - Harvey's Office -
Billy Bentley
Man in Suit #2 -
Lennard Ridsdale
Man in Suit #3 -
Jordan Ford Silver
Assistant Director - Pump It Up Show -
Oscar Salem
2nd Assistant Director - Pump It Up Show -
Viviane Bossina
Sue's Assistant -
Matthew Luret
Floor Runner -
Jana Bittnerová
Maria -
Olivier Raynal
Alan - 2nd Agent -
Tiffany Hofstetter
Stylist -
Nicolas Royer
Guy in the Elevator -
Nathan Rippy
Assistant Director - New Year's Eve Show -
Manon Arizmendi
Little Girl - New Year's Eve Show -
Virginie Kotlinski
Mother - New Year's Eve Show -
Brett Gillen
Director of Photography - New Year's Eve Show -
Charlotte Marquardt
Screaming Woman
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Tim Bevan (Production)
Producer -
Eric Fellner (Production)
Producer -
Valérie Deloof (Sound)
Sound Designer -
Frédérique Arguello (Costume & Make-Up)
Hair Department Head -
Laure Cochener (Production)
Casting -
Stephane Girondeaud (Crew)
Stunts -
Arnaud Denis (Art)
Art Direction -
Stanislas Reydellet (Art)
Production Design -
Stéphane Thiébaut (Sound)
Sound Re-Recording Mixer -
Emmanuelle Youchnovski (Costume & Make-Up)
Costume Designer -
Nicolas Royer (Production)
Executive Producer -
Cécilia Blom (Art)
Set Decoration -
Olivier Afonso (Costume & Make-Up)
Special Effects Makeup Artist -
Guillaume Le Gouez (Visual Effects)
Visual Effects Supervisor -
Marianne Huet (Directing)
Script Supervisor -
Stella Libert (Camera)
First Assistant Camera -
Bryan Jones (Visual Effects)
Visual Effects Supervisor -
Dave Elsey (Costume & Make-Up)
Prosthetic Supervisor -
Patrick Christensen (Sound)
ADR Mixer -
Raffertie (Sound)
Original Music Composer -
Benjamin Kračun (Camera)
Director of Photography -
Richard Martin (Costume & Make-Up)
Prosthetics Sculptor -
Emmanuelle Villard (Sound)
Sound Mixer -
Abraham Goldblat (Crew)
Post Production Supervisor -
Brian Kinney (Costume & Make-Up)
Special Effects Makeup Artist -
Lou Elsey (Costume & Make-Up)
Prosthetic Supervisor -
Oriane Cattiaux (Costume & Make-Up)
Makeup Artist -
Coralie Fargeat (Writing)
Writer -
Pierre Olivier Persin (Costume & Make-Up)
Makeup Effects Designer -
Grégory Vincent (Sound)
Foley Artist
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Official Clip
- Clip
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Official Teaser
- Teaser
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Official Trailer
- Trailer
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Mark it in your calendar
- Teaser
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TIFF 2024 Q&A
- Featurette
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The hype is real
- Featurette
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Breaking Down THE SUBSTANCE's Shrimp Scene
- Featurette
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Official Clip - Lucky Day
- Clip
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Pretty Girls Should Always Smile - The Substance | CLIP
- Clip
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