In his announcement on social media, he thanked fans for their long-term support and noted how this wouldn't actually be the end of his career. As of September, he's beginning work on a "new game" in a "new environment".
"I hope to create fun, beautiful games that are as memorable as, or even more memorable than, the ones I have created so far. Please stay tuned for my next creation."
Itsuno was the director on Capcom's recently released action-RPG Dragon's Dogma 2. He also worked on series like Power Stone in his earlier years.